What is Spatial Biology in a CRO Context?

Spatial biology has redefined how scientists visualize gene and protein expression within the tissue microenvironment. By maintaining spatial context, researchers can extract deeper, more clinically relevant insights from samples across oncology, immunology, neuroscience, and more.

As a leading contract research organization (CRO) specializing in spatial biology, BioChain bridges innovation and implementation. Our spatial biology CRO services combine high-throughput platforms with tissue quality expertise and robust bioinformatics to accelerate discovery, biomarker validation, and translational research outcomes.

Whether you need high-fidelity sample prep or end-to-end support for clinical trial integration, BioChain is your trusted CRO partner for everything spatial biology.

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Platforms We Support

Spatial is complicated. We make it simple.

BioChain supports the industry’s leading spatial transcriptomics and proteomics technologies — each tailored to specific research goals:

10x Genomics Xenium Spatial Analyzer: Single-cell resolution, high-plex RNA profiling

DISCOVER XENIUM

10x Genomics Visium Spatial Multiomics: Whole transcriptome mapping with tissue morphology integration

DISCOVER VISIUM

NanoString GeoMx® Digital Spatial Profiler: Flexible ROI selection, ideal for FFPE samples

DISCOVER GEOMX

Contract research in spatial biology means tailored guidance for project design, execution, and analysis. We’re here to guide you through the use of each assay we offer, as well as offer the necessary products to support your project – whether they be custom tissue samples or advanced data processing.

Our Spatial Biology CRO Services

We offer fully customizable, end-to-end support for spatial biology studies—from early discovery to translational and clinical applications.

Tissue & Sample Preparation. Cryo, FFPE, and fresh-frozen processing, sectioning, staining, and TMA construction. Tissue Quality Assessment (TQA) ensures optimal performance.
Spatial Transcriptomics & Proteomics. High-resolution spatial mapping of RNA and proteins using Xenium, Visium, and GeoMx platforms.
Bioinformatics & Data Analysis. Advanced data processing pipelines and spatial data visualization. Includes deconvolution, clustering, differential expression, and image-based analytics.
Biomarker Discovery & Validation. From exploratory biomarker screens to preclinical validation and stratification.
Clinical & Translational Research Support. Protocol optimization, regulatory-grade tissue handling, and sample-to-data solutions for clinical trial integration.

These workflows are core to BioChain’s support of cutting edge molecular and clinical discovery.

Looking for a CRO partner for Xenium, Visium, or GeoMx? We speak the language of both discovery and compliance.

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Why Partner with BioChain?

Choosing the right CRO for spatial biology means finding a team that understands both the complexity of spatial assays and the operational discipline needed to deliver reproducible, high-quality results.

Here’s why global clients trust BioChain:

Multiplatform Expertise: We don’t just run assays—we optimize them for your biological question and tissue type.
Proven Track Record: Supported thousands of FFPE and fresh-frozen spatial projects; extensive experience across oncology, CNS, infectious disease, and rare indications.
End-to-End Integration: In-house sample prep, histology, assay execution, and data analytics.
Rapid Turnaround: Streamlined workflows, expert staff, and optimized logistics deliver faster project completion.

Reproducible, High-Quality Data: Stringent QC pipelines and tissue scoring ensure consistency and comparability.

Use Cases & Applications

BioChain’s spatial biology CRO services support a wide range of research and drug development goals, including:

Oncology: Tumor microenvironment mapping, immune cell profiling, and checkpoint biomarker analysis
Neuroscience: Regional expression in brain tissue, cell state discovery, neuroinflammation tracking
Infectious Disease: Spatial pathogen-host interactions, granuloma formation studies
Rare Disease & Developmental Biology: Spatial gene expression atlases, developmental trajectory analysis
Clinical Trials: Biomarker stratification, retrospective tissue cohort studies, exploratory endpoint development